Classification criteria for lupus
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Classification criteria for lupus
The following criteria are used to distinguish lupus (systemic lupus erythematosus, or SLE) from other autoimmune and rheumatic diseases.
A person with 4 of these 11 conditions can be classified as having lupus. Symptoms may be present all at once or appear in succession over a period of time.1
- Butterfly (malar
) rash on cheeks - Rash on face, arms, neck, torso (discoid rash)
- Skin rashes that result from exposure to sunlight or ultraviolet light (photosensitivity)
- Mouth or nasal sores (ulcers), usually painless
- Joint swelling, stiffness, pain involving two or more joints (arthritis)
- Inflammation of the membranes surrounding the lungs (pleuritis) or heart (pericarditis). This inflammation is called serositis.
- Abnormalities in urine, such as increased protein or clumps of red blood cells or kidney cells, called cell casts, in the urine
- Nervous system problems, such as seizures or psychosis, without known cause
- Problems with the blood, such as reduced numbers of red blood cells (anemia), platelets, or white blood cells
- Positive antinuclear antibody (ANA) test
- Laboratory tests indicating increased autoimmune activity (antibodies against normal tissue)
References
Citations
Petri MA (2005). Systemic lupus erythematosus: Clinical aspects. In WJ Koopman, LW Moreland, eds., Arthritis and Allied Conditions: A Textbook of Rheumatology, 15th ed., vol. 2, pp.1473–1496. Philadelphia: Lippincott Williams and Wilkins.
Credits
| Author | Shannon Erstad, MBA/MPH |
| Author | Ralph Poore |
| Editor | Kathleen M. Ariss, MS |
| Associate Editor | Michele Cronen |
| Associate Editor | Pat Truman |
| Associate Editor | Terrina Vail |
| Primary Medical Reviewer | Kathleen Romito, MD - Family Medicine |
| Specialist Medical Reviewer | Stanford M. Shoor, MD - Rheumatology |
| Last Updated | May 17, 2006 |
| Last updated: | May 17, 2006 |
|---|---|
| Author: | Ralph Poore |
| Reviewed By: | Kathleen Romito, MD - Family Medicine, Stanford M. Shoor, MD - Rheumatology |
| Editors: | Kathleen M. Ariss, MS, Terrina Vail |
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