How common is juvenile rheumatoid arthritis?


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How common is juvenile rheumatoid arthritis?


About 1 in 1,000 children have juvenile rheumatoid arthritis (JRA).1 There are three types of juvenile rheumatoid arthritis. Pauciarticular JRA (also known as oligoarthritis) and polyarticular JRA (also known as polyarthritis) are most common in girls. Systemic JRA is equally common in boys and girls.2

The three types of JRA affect children at the following rates:3

  • About 60% of all children with JRA have pauciarticular symptoms during the first 6 months. While as many as 1 in 5 of these children goes on to develop polyarticular symptoms, most continue to have less than 4 joints affected over time.4
  • About 30% of all children with JRA have polyarticular symptoms.
  • About 10% of all children with JRA have systemic symptoms.

Juvenile rheumatoid arthritis can occur at higher rates among certain ethnic groups as well as in some geographic areas. Environmental and genetic factors are thought to be responsible, though researchers have yet to confirm this theory.4

  • In the United States, children of African or European descent have similar rates of JRA.
  • Some Native American populations have increased rates of JRA. In British Columbia, Canada, Native American children are over 3 times more likely to develop JRA than children of European descent in the same geographic area.

References


Citations

  1. Miller ML, Cassidy JT (2004). Juvenile rheumatoid arthritis. In RE Behrman et al., eds., Nelson Textbook of Pediatrics, 17th ed., chap. 145, pp. 799–805. Philadelphia: Saunders.

  2. Wallace CA, Sherry DD (2003). Juvenile rheumatoid arthritis. In CD Rudolph et al., eds., Rudolph's Pediatrics, 21st ed., chap 12.4, pp. 836–840. New York: McGraw-Hill.

  3. Cassidy JT (2005). Juvenile rheumatoid arthritis. In ED Harris Jr et al., eds., Kelley's Textbook of Rheumatology, 7th ed., vol. 2, pp. 1579–1596. Philadelphia: Elsevier Saunders.

  4. Warren RW, et al. (2005). Juvenile idiopathic arthritis (Juvenile rheumatoid arthritis). In WJ Koopman, LW Moreland, eds., Arthritis and Allied Conditions, 15th ed., vol. 1, pp. 1277–1300. Philadelphia: Lippincott Williams and Wilkins.

Credits


Author Shannon Erstad, MBA/MPH
Editor Kathleen M. Ariss, MS
Associate Editor Tracy Landauer
Primary Medical Reviewer Michael J. Sexton, MD

- Pediatrics
Specialist Medical Reviewer Ross E. Petty, MD, PhD, FRCPC

- Pediatric Rheumatology
Last Updated June 30, 2006

Healthwise Logo
Last updated: June 30, 2006
Author: Shannon Erstad, MBA/MPH
Reviewed By: Michael J. Sexton, MD - Pediatrics, Ross E. Petty, MD, PhD, FRCPC - Pediatric Rheumatology
Editors: Kathleen M. Ariss, MS, Tracy Landauer

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