Wernicke-Korsakoff syndrome

Content provided by Healthwise

Wernicke-Korsakoff syndrome

Wernicke-Korsakoff syndrome is a serious brain disorder that can develop in people who drink alcohol excessively over time. Symptoms include blurred vision, rapid movement of the eyes, and difficulty walking.

Wernicke-Korsakoff syndrome is a combination of two conditions: Wernicke syndrome and Korsakoff syndrome.

Wernicke syndrome is caused by thiamine (vitamin B₁) deficiency. Symptoms such as blurred vision may go away if a person stops drinking and takes thiamine supplements.
Korsakoff syndrome is caused by changes in the brain that result from long-term alcohol use. Symptoms include confusion and memory loss, especially of recent events, which often lead the person to make up events (confabulation) to fill the memory gaps. The effects of Korsakoff syndrome may be permanent.

Treatment for Wernicke-Korsakoff syndrome includes replacement of thiamine, proper nutrition and body fluids (hydration), and avoiding alcohol use.

Credits

Author	Jeannette Curtis
Author	Caroline Rea, RN, BS, MS
Editor	Kathleen M. Ariss, MS
Editor	Susan Van Houten, RN, BSN, MBA
Associate Editor	Tracy Landauer
Associate Editor	Pat Truman
Primary Medical Reviewer	Patrice Burgess, MD - Family Medicine
Primary Medical Reviewer	Adam Husney, MD - Family Medicine
Primary Medical Reviewer	Kathleen Romito, MD - Family Medicine
Last Updated	May 25, 2007

Last updated:	May 25, 2007
Author:	Caroline Rea, RN, BS, MS
Reviewed By:	Kathleen Romito, MD - Family Medicine
Editors:	Susan Van Houten, RN, BSN, MBA, Pat Truman

This information is not intended to replace the advice of a doctor. By using AOL Body, you indicate that you have read, understood, and agreed to our Terms of Service, and AOL Body Advertising Policy. Read more about our content partners.