Rubella Test

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Test Overview

A rubella blood test detects antibodies that are made by the immune system to help kill the rubella virus. Once produced, the antibodies remain in the bloodstream for years. The presence of certain antibodies indicates a recent infection, a past infection, or that you have been vaccinated against the disease.

• The presence of IgM antibodies means you have a current or recent rubella infection.
• The presence of IgG antibodies means you have immunity against the infection. This immunity could have been received either through vaccination for rubella or a past rubella infection.

Rubella (also called German measles or 3-day measles) usually does not cause long-term problems. However, a woman infected with the rubella virus during pregnancy can transmit the disease to her baby (fetus). And serious birth defects called congenital rubella syndrome (CRS) could develop during the first trimester. Birth defects of CRS include cataracts and other eye problems, hearing impairment, and heart disease. Miscarriage and stillbirth are also possible consequences for pregnant women. The vaccination to prevent rubella protects against these complications.

A rubella test is usually done for a woman who is or wants to become pregnant to determine whether she is at risk for rubella. Several laboratory methods can be used to detect rubella antibodies in the blood. The most commonly used method is the enzyme-linked immunosorbent assay (ELISA, EIA).

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Last updated:	October 02, 2006
Author:	Debby Golonka, MPH
Reviewed By:	Michael J. Sexton, MD - Pediatrics, W. David Colby, MSc, MD, FRCPC - Infectious Disease
Editors:	Susan Van Houten, RN, BSN, MBA, Tracy Landauer